MYO5B Antikörper (N-Term)

Produktnummer ABIN966630

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-MYO5B Antikörper (ABIN966630) detektiert spezifisch MYO5B in IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für MYO5B Antikörper (N-Term) (ABIN966630)

Target: MYO5B (Myosin VB (MYO5B))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYO5B Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktdetails anti-MYO5B Antikörper

Bindungsspezifität: N-Term

Aufreinigung: Purified by antigen-specific affinity chromatography.

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human Myosin-5B (Myosin Vb)

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: This antibody is stored in PBS, 0.01% sodium azide and 50% glycerol.

Lagerung: -20 °C

Referenzen für anti-MYO5B Antikörper (ABIN966630)

Szperl, Golachowska, Bruinenberg, Prekeris, Thunnissen, Karrenbeld, Dijkstra, Hoekstra, Mercer, Ksiazyk, Wijmenga, Wapenaar, Rings, van IJzendoorn: "Functional characterization of mutations in the myosin Vb gene associated with microvillus inclusion disease." in: Journal of pediatric gastroenterology and nutrition, Vol. 52, Issue 3, pp. 307-13, (2011) (PubMed).

Details zu MYO5B

Target: MYO5B (Myosin VB (MYO5B))

Andere Bezeichnung: MYO5B

Hintergrund: MYO5B(Myosin-5B)(Myosin Vb)interacts with RAB11FIP2. MYO5B(Myosin-5B)(Myosin Vb) has a role in in glutamate receptor GluR1 trafficking. The myosin Vb functions in traffic between peripheral and pericentrosomal compartments. The protein contains 1 dilute domain and 6 IQ domains. It also contains 1 myosin head-like domain. The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament