MYO5B Antikörper (AA 50-100)

Produktnummer ABIN7451161

Produktdetails anti-MYO5B Antikörper

Target: MYO5B (Myosin VB (MYO5B))

Bindungsspezifität: AA 50-100

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYO5B Antikörper ist unkonjugiert

Applikation: Immunoprecipitation (IP)

Verwendungszweck: Rabbit anti-MYO5B Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: Between AA 50 and 100

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. ABIN7451161 has not performed satisfactorily when used for WB of MYO5B in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of MYO5B.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu MYO5B

Target: MYO5B (Myosin VB (MYO5B))

Andere Bezeichnung: MYO5B (MYO5B Produkte)

Synonyme: AI661750 antikoerper, mKIAA1119 antikoerper, Myr6 antikoerper, myosin VB antikoerper, myosin Vb antikoerper, MYO5B antikoerper, Myo5b antikoerper

Hintergrund: Background: Myosin 5B may be involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. MYO5B is required in a complex with RAB11A and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Also, together with RAB11A, MYO5B participates in CFTR trafficking to the plasma membrane and TF (transferrin) recycling in nonpolarized cells. Together with RAB11A and RAB8A it participates in epithelial cell polarization. Together with RAB25 MYO5B regulates transcytosis [taken from the Universal Protein Resource (UniProt) Q9ULV0].

Gen-ID: 4645

UniProt: Q9ULV0