Der not_set-Monoklonal Anti-Lipoprotein Lipase-Antikörper wurde für WB und ELISA validiert. Er ist geeignet zum Nachweis von Lipoprotein Lipase in Proben aus Human und Rind (Kuh).
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LPL
Reaktivität: Human
WB, IP
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
Western blot (1:1000) and ELISA (1:2000~5000) in lipid metabolic research.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
1mg/ml
Buffer
PBS, pH 7.4
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Target
Lipoprotein Lipase (LPL)
Andere Bezeichnung
LPL
Hintergrund
Lipoprotein lipase (LPL) is the central enzyme in plasma triglyceride hydrolysis and is secreted by macrophages in the subendothelial space. Evidence has been provided that LPL produced by macrophages in the vessel wall exerts proatherogenic effects. The atherogenic effects of LPL have been mainly attributed to its ability to favor lipid accumulation within macrophages present in the atherosclerotic lesion. Recently, it has also been shown that LPL promote the development of atherosclerosis through facilitation of monocyte adhesion to endothelial cells, stimulation of tumor necrosis factor alpha (TNF ) secretion and induction of vascular smooth muscle cell proliferation.