KLHL22 Antikörper

Produktnummer ABIN966459

Dieses Anti-KLHL22-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von KLHL22 in WB und IF. Geeignet für Human. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für KLHL22 Antikörper (ABIN966459)

Target: KLHL22 (Kelch-Like 22 (KLHL22))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser KLHL22 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Klon: 7B10

Produktdetails anti-KLHL22 Antikörper

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human KLHL22 expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western Bloting: 1/500 - 1/2000.
Immunofluorescence: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Referenzen für anti-KLHL22 Antikörper (ABIN966459)

Maruyama, Sugano: "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides." in: Gene, Vol. 138, Issue 1-2, pp. 171-4, (1994) (PubMed).

Details zu KLHL22

Target: KLHL22 (Kelch-Like 22 (KLHL22))

Andere Bezeichnung: KLHL22

Hintergrund: KLHL22 (kelch-like protein 22) is a 634 amino acid protein that is related to the Drosophilakelch protein, which is required to maintain Actin organization in ovarian ring canals. Mutations affecting Kelch function result in the failure of Kelch to associate with the ring canals and subsequent female sterility. Human KLHL22 protein contains six kelch repeats and one BTB (POZ) domain. The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. There are two isoforms of KLHL22 that are produced as a result of alternative splicing events.
Synonyms: KELCHL, KLHL22

Molekulargewicht: 72kDa

Gen-ID: 84861