Glutamate Receptor 3 Antikörper

Produktnummer ABIN966225

Zitiert in 1 Publikation. Der Maus Monoklonal anti-Glutamate Receptor 3 Antikörper (Klon 1D2) (ABIN966225) detektiert spezifisch Glutamate Receptor 3 in WB, ELISA und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Glutamate Receptor 3 Antikörper (ABIN966225)

Target: Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Glutamate Receptor 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Klon: 1D2

Produktdetails anti-Glutamate Receptor 3 Antikörper

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human GRIA3 expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Referenzen für anti-Glutamate Receptor 3 Antikörper (ABIN966225)

Am: "Trust in Nanotechnology? On Trust as Analytical Tool in Social Research on Emerging Technologies." in: Nanoethics, Vol. 5, Issue 1, pp. 15-28, (2011) (PubMed).

Details zu Glutamate Receptor 3

Target: Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))

Andere Bezeichnung: GRIA3

Hintergrund: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA, R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties.
Synonyms: GLUR3, GLURC, GluA3, MRX94, GLUR-C, GLUR-K3

Molekulargewicht: 101kDa

Gen-ID: 2892

Pathways: PI3K-Akt Signalweg, cAMP Metabolic Process, Synaptic Membrane