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GDF15 Antikörper (Middle Region)

Dieses Anti-GDF15-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GDF15 in IHC. Geeignet für Maus und Ratte. Dieses Primary Antibody wurde in 7+ Publikationen zitiert.
Produktnummer ABIN966198

Kurzübersicht für GDF15 Antikörper (Middle Region) (ABIN966198)

Target

Alle GDF15 Antikörper anzeigen
GDF15 (Growth Differentiation Factor 15 (GDF15))

Reaktivität

  • 117
  • 41
  • 26
  • 1
  • 1
Maus, Ratte

Wirt

  • 107
  • 26
  • 3
  • 2
  • 1
Kaninchen

Klonalität

  • 104
  • 32
  • 2
Polyklonal

Konjugat

  • 83
  • 18
  • 10
  • 6
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser GDF15 Antikörper ist unkonjugiert

Applikation

  • 113
  • 68
  • 62
  • 28
  • 23
  • 15
  • 13
  • 13
  • 7
  • 6
  • 5
  • 3
  • 2
  • 1
  • 1
Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 15
    • 13
    • 12
    • 9
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    Immunogen

    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to middle residues of mouse GDF-15 (Growth Differentiation factor 15)
  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Lagerung

    4 °C
  • Iguchi, Chrysovergis, Lee, Baek, Langenbach, Eling: "A reciprocal relationship exists between non-steroidal anti-inflammatory drug-activated gene-1 (NAG-1) and cyclooxygenase-2." in: Cancer letters, Vol. 282, Issue 2, pp. 152-8, (2009) (PubMed).

    Cekanova, Lee, Donnell, Sukhthankar, Eling, Fischer, Baek: "Nonsteroidal anti-inflammatory drug-activated gene-1 expression inhibits urethane-induced pulmonary tumorigenesis in transgenic mice." in: Cancer prevention research (Philadelphia, Pa.), Vol. 2, Issue 5, pp. 450-8, (2009) (PubMed).

    Ding, Mracek, Gonzalez-Muniesa, Kos, Wilding, Trayhurn, Bing: "Identification of macrophage inhibitory cytokine-1 in adipose tissue and its secretion as an adipokine by human adipocytes." in: Endocrinology, Vol. 150, Issue 4, pp. 1688-96, (2009) (PubMed).

    Zimmers, Jin, Gutierrez, Acosta, McKillop, Pierce, Koniaris: "Effect of in vivo loss of GDF-15 on hepatocellular carcinogenesis." in: Journal of cancer research and clinical oncology, Vol. 134, Issue 7, pp. 753-9, (2008) (PubMed).

    Noorali, Kurita, Woolcock, de Algara, Lo, Paralkar, Hoodless, Vielkind: "Dynamics of expression of growth differentiation factor 15 in normal and PIN development in the mouse." in: Differentiation; research in biological diversity, Vol. 75, Issue 4, pp. 325-36, (2007) (PubMed).

    Oxburgh, Chu, Michael, Robertson: "TGFbeta superfamily signals are required for morphogenesis of the kidney mesenchyme progenitor population." in: Development (Cambridge, England), Vol. 131, Issue 18, pp. 4593-605, (2004) (PubMed).

    Zambrowicz, Abuin, Ramirez-Solis, Richter, Piggott, BeltrandelRio, Buxton, Edwards, Finch, Friddle, Gupta, Hansen, Hu, Huang, Jaing, Key, Kipp, Kohlhauff, Ma, Markesich, Payne, Potter, Qian, Shaw et al.: "Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 24, pp. 14109-14, (2003) (PubMed).

  • Target

    GDF15 (Growth Differentiation Factor 15 (GDF15))

    Andere Bezeichnung

    GDF-15

    Hintergrund

    GDF-15 (Growth Differentiation factor 15) is a transforming growth factor beta superfamily member induced following liver injury. GDF-15 is a homodimer and disulfide-linked by similarity. GDF-15 is secreted and highly expressed in liver. GDF-15 belongs to the TGF-beta family.
    Synonyms: Macrophage inhibiting cytokine-1(MIC-1)

    Pathways

    SARS-CoV-2 Protein Interaktom
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