FGF7 Antikörper (N-Term)

Produktnummer ABIN966138

Dieses Anti-FGF7-Antikörper ist ein Polyklonal-Antikörper zur Detektion von FGF7 in WB und IHC (p). Geeignet für Human. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für FGF7 Antikörper (N-Term) (ABIN966138)

Target: FGF7 (Fibroblast Growth Factor 7 (FGF7))

Reaktivität: Human

Wirt: Bitte anfragen

Klonalität: Polyklonal

Konjugat: Dieser FGF7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-FGF7 Antikörper

Bindungsspezifität: AA 51-65, N-Term

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminal of human FGF7 (51-65aa), identical to the related mouse and rat sequence.

Anwendungsinformationen

Applikationshinweise: WB: The detection limit for FGF7 is approximately 5ng/lane under non-reducing and reducing conditions.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: 0.2ml of distilled water will yield a concentration of 500µg/ml.

Buffer: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Lagerung: -20 °C

Referenzen für anti-FGF7 Antikörper (ABIN966138)

Eberlé, Dubreuil, Mattei, Devilard, Lopez: "The human PRR2 gene, related to the human poliovirus receptor gene (PVR), is the true homolog of the murine MPH gene." in: Gene, Vol. 159, Issue 2, pp. 267-72, (1995) (PubMed).

Kelley, Pech, Seuanez, Rubin, OBrien, Aaronson: "Emergence of the keratinocyte growth factor multigene family during the great ape radiation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 19, pp. 9287-91, (1992) (PubMed).

Details zu FGF7

Target: FGF7 (Fibroblast Growth Factor 7 (FGF7))

Andere Bezeichnung: FGF7

Hintergrund: Keratinocyte growth factor is a protein that in humans is encoded by the FGF7 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis.

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung