FANCG Antikörper (C-Term)

Produktnummer ABIN966129

Zitiert in 3+ Publikationen. Der Kaninchen Polyklonal anti-FANCG Antikörper (ABIN966129) detektiert spezifisch FANCG in IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für FANCG Antikörper (C-Term) (ABIN966129)

Target: FANCG (Fanconi Anemia Complementation Group G (FANCG))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FANCG Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktdetails anti-FANCG Antikörper

Bindungsspezifität: C-Term

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human FANCG (Fanconi anemia group G protein)

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C

Referenzen für anti-FANCG Antikörper (ABIN966129)

Meetei, Levitus, Xue, Medhurst, Zwaan, Ling, Rooimans, Bier, Hoatlin, Pals, de Winter, Wang, Joenje: "X-linked inheritance of Fanconi anemia complementation group B." in: Nature genetics, Vol. 36, Issue 11, pp. 1219-24, (2004) (PubMed).

Demuth, Wlodarski, Tipping, Morgan, de Winter, Thiel, Gräsl, Schindler, DAndrea, Altay, Kayserili, Zatterale, Kunze, Ebell, Mathew, Joenje, Sperling, Digweed: "Spectrum of mutations in the Fanconi anaemia group G gene, FANCG/XRCC9." in: European journal of human genetics : EJHG, Vol. 8, Issue 11, pp. 861-8, (2000) (PubMed).

Garcia-Higuera, Kuang, Näf, Wasik, DAndrea: "Fanconi anemia proteins FANCA, FANCC, and FANCG/XRCC9 interact in a functional nuclear complex." in: Molecular and cellular biology, Vol. 19, Issue 7, pp. 4866-73, (1999) (PubMed).

Details zu FANCG

Target: FANCG (Fanconi Anemia Complementation Group G (FANCG))

Andere Bezeichnung: FANCG

Hintergrund: DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. FANCG may be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. FANCG is a andidate tumor suppressor gene. FANCG belongs to the multisubunit FA complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. The complex is not found in FA patients. The major form is nuclear. The minor form is cytoplasmic. Highly expressed in testis and thymus. Found in lymphoblasts. Defects in FANCG are a cause of Fanconi anemia (FA)
Synonym: XRCC9 (DNA repair protein XRCC9)

Pathways: DNA Reparatur