EPH Receptor B6 Antikörper

Produktnummer ABIN966077

Der Maus Monoklonal Anti-EPH Receptor B6-Antikörper wurde für WB, ELISA und IHC validiert. Er ist geeignet, EPH Receptor B6 in Proben von Human zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für EPH Receptor B6 Antikörper (ABIN966077)

Target: EPH Receptor B6 (EPHB6)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser EPH Receptor B6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Klon: 8E7H12

Produktdetails anti-EPH Receptor B6 Antikörper

Aufreinigung: Purified

Immunogen: Purified recombinant fragment of EphB6 expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Referenzen für anti-EPH Receptor B6 Antikörper (ABIN966077)

Ogawa, Wada, Okada, Harada, Nakajima, Pasquale, Tsuyama: "EphB2 and ephrin-B1 expressed in the adult kidney regulate the cytoarchitecture of medullary tubule cells through Rho family GTPases." in: Journal of cell science, Vol. 119, Issue Pt 3, pp. 559-70, (2006) (PubMed).

Matsuoka, Obama, Kelly, Matsui, Nakamoto: "Biphasic functions of the kinase-defective Ephb6 receptor in cell adhesion and migration." in: The Journal of biological chemistry, Vol. 280, Issue 32, pp. 29355-63, (2005) (PubMed).

Details zu EPH Receptor B6

Target: EPH Receptor B6 (EPHB6)

Andere Bezeichnung: EphB6

Hintergrund: EPH receptor B6 (EphB6), with 1006-amino acid protein(~ 110 kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. Eph receptors and ephrin ligands are membrane-bound cell-cell communication molecules with well-defined functions in development. EphB6 is expressed both in a variety of embryonic and adult tissues. EphB6 is a unique member in the Eph family of receptor tyrosine kinases in that its kinase domain contains several alterations in conserved amino acids and is catalytically inactive. EphB6 can both positively and negatively regulate cell adhesion and migration and tyrosine phosphorylation of the receptor by an Src family kinase acts as the molecular switch for the functional transition.
Synonyms: HEP, MGC129910, MGC129911

Gen-ID: 2051

Pathways: RTK Signalweg, Hormone Transport