EIF4E Antikörper
(1 reference)-
- Target Alle EIF4E Antikörper anzeigen
- EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser EIF4E Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)
- Aufreinigung
- Ascitic fluid
- Immunogen
- Purified recombinant fragment of human EIF4E expressed in E. Coli.
- Klon
- 5D11
- Isotyp
- IgG1
- Top Product
- Discover our top product EIF4E Primärantikörper
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anti-Eukaryotic Translation Initiation Factor 4E (EIF4E) (AA 121-217) antibody
EIF4E Reaktivität: Human, Ratte WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4E (EIF4E) antibodyEIF4E Reaktivität: Human WB, IHC, ELISA, FACS, ICC Wirt: Maus Monoclonal 5D11 unconjugated
anti-Eukaryotic Translation Initiation Factor 4E (EIF4E) (AA 1-100) antibodyEIF4E Reaktivität: Human WB, IHC, IF, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4E (EIF4E) (AA 1-217) antibodyEIF4E Reaktivität: Human, Ratte, Maus, Hund, Huhn, Frosch WB, BI Wirt: Maus Monoclonal 87-eIF unconjugated
anti-Eukaryotic Translation Initiation Factor 4E (EIF4E) (pSer209) antibodyEIF4E Reaktivität: Human, Ratte, Maus WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4E (EIF4E) (C-Term) antibodyEIF4E Reaktivität: Human, Ratte, Maus WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4E (EIF4E) antibodyEIF4E Reaktivität: Human WB, IHC, ELISA, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4E (EIF4E) (pSer209) antibodyEIF4E Reaktivität: Human, Ratte, Maus, Zebrafisch (Danio rerio) WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4E (EIF4E) antibodyEIF4E Reaktivität: Human, Maus WB, IF Wirt: Maus Monoclonal 163CT48-1-9 unconjugated
anti-Eukaryotic Translation Initiation Factor 4E (EIF4E) antibodyEIF4E Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB23009 unconjugated
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- Applikationshinweise
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Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
Immunofluorescence: 1/200 - 1/1000.
Flow cytometry: 1/200 - 1/400.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
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: "Kinetic mechanism for assembly of the m7GpppG.eIF4E.eIF4G complex." in: The Journal of biological chemistry, Vol. 283, Issue 37, pp. 25227-37, (2008) (PubMed).
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: "Kinetic mechanism for assembly of the m7GpppG.eIF4E.eIF4G complex." in: The Journal of biological chemistry, Vol. 283, Issue 37, pp. 25227-37, (2008) (PubMed).
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- Target
- EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))
- Andere Bezeichnung
- EIF4E (EIF4E Produkte)
- Hintergrund
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EIF4E, a protein modulates translation of maternal mRNAs in early embryos before the onset of zygotic transcription. eIF4E also influences the overall rate of translation. eIF4E binds to the 7 methyl GTP cap structure of eukaryotic mRNAs. Phosphorylation of eIF4E on serine 209 regulates the affinity of this protein for the 7 methyl GTP cap and/or RNA. Phosphorylation also enhances the interaction of eIF4E with eIF4G, which form a complex known as eIF4F. eIF4E phosphorylation is correlated with increased translational rate in a number of cell types. Several kinases are currently being investigated as potential regulators of eIF4E including PKC and/or the MAP kinase activated Mnk.
Synonyms: CBP, EIF4F, EIF4E1, EIF4EL1, MGC111573, EIF4E - Molekulargewicht
- 25kDa
- Gen-ID
- 1977
- Pathways
- BCR Signaling
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