Decorin Antikörper (Isoform d)

Produktnummer ABIN965978

Der Kaninchen Polyklonal Anti-Decorin-Antikörper wurde für IHC validiert. Er ist geeignet, Decorin in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für Decorin Antikörper (Isoform d) (ABIN965978)

Target: Decorin (DCN)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Decorin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktdetails anti-Decorin Antikörper

Bindungsspezifität: Isoform d

Aufreinigung: Purified by antigen-specific affinity chromatography.

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human DCN (decorin isoform d precursor) Or dermatan sulphate proteoglycans II, bone proteoglycan II, proteoglycan core protein, small leucinerich protein 1B.

Anwendungsinformationen

Applikationshinweise: ELISA, Western blotting: 1µg/ml for 2hrs.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: This antibody is stored in PBS, 50% glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Referenzen für anti-Decorin Antikörper (ABIN965978)

Al-Mansi, Abdel: "Recovery of nickel oxide from spent catalyst." in: Waste management (New York, N.Y.), Vol. 22, Issue 1, pp. 85-90, (2002) (PubMed).

Details zu Decorin

Target: Decorin (DCN)

Andere Bezeichnung: DCN

Hintergrund: The DCN(decorin isoform d) is a small cellular or pericellular matrix proteoglycan that is closely related in structure to biglycan protein. The protein and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils,and plays a role in matrix assembly. It contains one attached glycosaminoglycan chain. This protein is capable of suppressing the growth of various tumor cell lines. The decorin supports adhesion and activation of human platelets. The decorin can disrupt glucose and TGFbeta/Smad-dependent transcription in mesangial cells through a mechanism that involves an increase in Ca(2+) signalling, the activation of Ca(2+)/calmodulin-dependent protein kinase II and phosphorylation of Smad2

Pathways: Glycosaminoglycan Metabolic Process