Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

CD31 Antikörper

Dieses Monoklonal-Antikörper erkennt spezifisch CD31 in WB, IHC und ELISA. Er zeigt eine Reaktivität gegenüber Human und wurde in 3+ Publikationen erwähnt.
Produktnummer ABIN965785

Kurzübersicht für CD31 Antikörper (ABIN965785)

Target

Alle CD31 (PECAM1) Antikörper anzeigen
CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Reaktivität

  • 389
  • 154
  • 80
  • 67
  • 44
  • 36
  • 21
  • 20
  • 11
  • 7
  • 4
  • 4
  • 4
  • 1
  • 1
  • 1
Human

Wirt

Bitte anfragen

Klonalität

  • 350
  • 146
  • 8
  • 1
Monoklonal

Konjugat

  • 199
  • 43
  • 33
  • 25
  • 19
  • 15
  • 15
  • 15
  • 15
  • 15
  • 15
  • 13
  • 6
  • 6
  • 5
  • 5
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CD31 Antikörper ist unkonjugiert

Applikation

  • 272
  • 247
  • 197
  • 133
  • 79
  • 70
  • 48
  • 36
  • 34
  • 33
  • 26
  • 23
  • 22
  • 13
  • 12
  • 9
  • 6
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • Spezifität

    Ni-NTA purified recombinant CD31 expressed in E. Coli strain BL21 (DE3)

    Aufreinigung

    Antibodies are purified by protein A affinity chromatography

    Isotyp

    IgG1
  • Applikationshinweise

    Western Blot: 1: 500- 1: 2,000
    IHC(P): 1: 500- 1: 2,000
    ELISA: Propose dilution 1: 10,000.
    Determining optimal working dilutions by titration test.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Lagerung

    -20 °C
  • Mayr, Zou, Zhang, Dietrich, Hu, Xu: "Accelerated arteriosclerosis of vein grafts in inducible NO synthase(-/-) mice is related to decreased endothelial progenitor cell repair." in: Circulation research, Vol. 98, Issue 3, pp. 412-20, (2006) (PubMed).

    Bingle, Lewis, Corke, Reed, Brown: "Macrophages promote angiogenesis in human breast tumour spheroids in vivo." in: British journal of cancer, Vol. 94, Issue 1, pp. 101-7, (2006) (PubMed).

    Wynne, Ball, McLellan, Dockery, Zimmermann, Moore: "Mouse pregnancy-specific glycoproteins: tissue-specific expression and evidence of association with maternal vasculature." in: Reproduction (Cambridge, England), Vol. 131, Issue 4, pp. 721-32, (2006) (PubMed).

  • Target

    CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

    Andere Bezeichnung

    CD31

    Hintergrund

    CD31, also known as platelet endothelial cell adhesion molecule 1 (PECAM1), is a type I integral membrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors.It is constitutively expressed on the surface of endothelial cells, and concentrated at the junction between them. The antibody reacts with the murine form of the Platelet-Endothelial Cell Adhesion Molecule. The reactivity of the antibody is restricted to the isoform of the molecule that is selectively expressed by endothelial cells.The antigen is predominantly present at the lateral borders of endothelial cells as described for human PECAM-1.It is also weakly expressed on many peripheral lymphoid cells and platelets. CD31 has been used to measure angiogenesis in association with tumor recurrence. Other studies have also indicated that CD31 and CD34 can be used as markers for myeloid progenitor cells and recognize different subsets of myeloid leukemia infiltrates (granular sarcomas).

    Gen-ID

    5175

    Pathways

    Regulation of Actin Filament Polymerization
Sie sind hier:
Chat with us!