CD31 Antikörper (AA 28-315)
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- Target Alle CD31 (PECAM1) Antikörper anzeigen
- CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))
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Bindungsspezifität
- AA 28-315
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD31 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA
- Kreuzreaktivität
- Human
- Aufreinigung
- Protein G purified
- Immunogen
- Recombinant Human CD31 protein (28-315AA)
- Klon
- 9E6E12
- Isotyp
- IgG2a
- Top Product
- Discover our top product PECAM1 Primärantikörper
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anti-Platelet/endothelial Cell Adhesion Molecule (PECAM1) (AA 601-680) antibody
PECAM1 Reaktivität: Human, Maus, Ratte, Kaninchen, Schwein, Hund FACS, WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Platelet/endothelial Cell Adhesion Molecule (PECAM1) (C-Term) antibodyPECAM1 Reaktivität: Human, Maus, Ratte, Hund, Affe WB, IHC Wirt: Ziege Polyclonal unconjugated
anti-Platelet/endothelial Cell Adhesion Molecule (PECAM1) antibodyPECAM1 Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Platelet/endothelial Cell Adhesion Molecule (PECAM1) (AA 28-382) antibodyPECAM1 Reaktivität: Human, Ratte FACS, WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Platelet/endothelial Cell Adhesion Molecule (PECAM1) (AA 681-738) antibodyPECAM1 Reaktivität: Human, Maus, Ratte, Kaninchen, Schwein, Rind (Kuh) FACS, WB, ELISA, IHC (p), IF (cc), IF (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Platelet/endothelial Cell Adhesion Molecule (PECAM1) antibodyPECAM1 Reaktivität: Human, Kaninchen, Cynomolgus FACS, WB, IHC, IF, StM Wirt: Maus Monoclonal JC-70A unconjugated
anti-Platelet/endothelial Cell Adhesion Molecule (PECAM1) antibodyPECAM1 Reaktivität: Human, Ratte FACS, WB, IHC, IF, StM Wirt: Maus Monoclonal C31-3 unconjugated
anti-Platelet/endothelial Cell Adhesion Molecule (PECAM1) (AA 625-738) antibodyPECAM1 Reaktivität: Human FACS, IHC, IF, StM Wirt: Maus Monoclonal PECAM1-3527 unconjugated
anti-Platelet/endothelial Cell Adhesion Molecule (PECAM1) antibodyPECAM1 Reaktivität: Human, Ratte, Kaninchen, Cynomolgus FACS, WB, IHC, StM Wirt: Maus Monoclonal C31-7 unconjugated
anti-Platelet/endothelial Cell Adhesion Molecule (PECAM1) (AA 29-738) antibodyPECAM1 Reaktivität: Human WB, ELISA, IP, IHC (p) Wirt: Maus Monoclonal 1D2-1A5 unconjugated
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- Applikationshinweise
- Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:500, IF:1:50-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))
- Andere Bezeichnung
- CD31 (PECAM1 Produkte)
- Synonyme
- CD31 antikoerper, CD31/EndoCAM antikoerper, GPIIA' antikoerper, PECA1 antikoerper, PECAM-1 antikoerper, endoCAM antikoerper, C85791 antikoerper, Cd31 antikoerper, Pecam antikoerper, platelet/endothelial cell adhesion molecule 1 antikoerper, platelet and endothelial cell adhesion molecule 1 antikoerper, pecam1 antikoerper, PECAM1 antikoerper, Pecam1 antikoerper
- Hintergrund
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Background: Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions (PubMed:19342684, PubMed:17580308). Tyr-690 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes (PubMed:19342684). Heterophilic interaction with CD177 plays a role in transendothelial migration of neutrophils (PubMed:17580308). Homophilic ligation of PECAM1 prevents macrophage-mediated phagocytosis of neighboring viable leukocytes by transmitting a detachment signal (PubMed:12110892). Promotes macrophage-mediated phagocytosis of apoptotic leukocytes by tethering them to the phagocytic cells, PECAM1-mediated detachment signal appears to be disabled in apoptotic leukocytes (PubMed:12110892). Modulates bradykinin receptor BDKRB2 activation (PubMed:18672896). Regulates bradykinin- and hyperosmotic shock-induced ERK1/2 activation in endothelial cells (PubMed:18672896). Induces susceptibility to atherosclerosis (By similarity).
Aliases: Platelet endothelial cell adhesion molecule, PECAM-1, EndoCAM, GPIIA', PECA1, CD31, PECAM1
- UniProt
- P16284
- Pathways
- Regulation of Actin Filament Polymerization
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