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YBX1 Antikörper

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch YBX1 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Borrelia burgdorferi.
Rockland
Produktnummer ABIN964624
Hersteller Produkt- Nr.: 200-401-c16

Kurzübersicht für YBX1 Antikörper (ABIN964624)

Target

Alle YBX1 Antikörper anzeigen
YBX1 (Y Box Binding Protein 1 (YBX1))

Reaktivität

  • 121
  • 62
  • 50
  • 20
  • 18
  • 18
  • 16
  • 6
  • 5
  • 5
  • 4
  • 4
  • 4
  • 2
  • 1
Borrelia burgdorferi

Wirt

  • 91
  • 32
Kaninchen

Klonalität

  • 82
  • 41
Polyklonal

Konjugat

  • 62
  • 7
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Dieser YBX1 Antikörper ist unkonjugiert

Applikation

  • 82
  • 41
  • 24
  • 22
  • 17
  • 15
  • 14
  • 13
  • 13
  • 9
  • 5
  • 5
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA
  • Hersteller Produkt- Nr.

    200-401-c16

    Hersteller

    Rockland

    Verwendungszweck

    DbpB Antibody

    Kreuzreaktivität (Details)

    This antibody is specific for Borrelia burgdorferi DbpB protein.

    Produktmerkmale

    Synonyms: rabbit anti-DbpB Antibody, Decorin-binding protein B, Borrelia burgdorferi DbpB, dbp-B, dbp B

    Aufreinigung

    This product was Protein-A purified and cross-adsorbed against MBP from monospecific antiserum by chromatography.

    Immunogen

    Immunogen: MBP-fusion protein corresponding to Borrelia burgdorferi Dbp-B protein.

    Immunogen Type: Recombinant Protein

    Isotyp

    IgG
  • Applikationshinweise

    Application Note: This protein-A purified antibody has been tested for use in ELISA and Western blotting. Specific conditions for reactivity should be optimized by the user. Expect a band approximately 17.9 kDa in size corresponding to Borrelia burgdorferi DbpB protein by Western blotting in the appropriate cell lysate or extract.

    Western Blot Dilution: 1:1,000

    Other: User Optimized

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Reconstitution Volume: 100 μL

    Reconstitution Buffer: Restore with deionized water (or equivalent)

    Konzentration

    1.0 mg/mL

    Buffer

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store vial at 4° C prior to restoration. For extended storage aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

    Haltbarkeit

    12 months
  • Target

    YBX1 (Y Box Binding Protein 1 (YBX1))

    Andere Bezeichnung

    DbpB

    Hintergrund

    Background: Decorin-binding protein B, or DbpB, binds to decorin, which may mediate the adherence of B.burgdorferi to collagen fibers in skin and other tissues. Spirochetal surface adhesions mediate attachment to decorin, a major component of the host extracellular matrix enabling bacteria to colonize in mammalian tissues. The spirochete migrates from the tick midgut during feeding to its salivary glands and are thus transmitted to the mammal host. This transition may be facilitated by changes in expression of some B. burgdorferi genes. It is believed that expression of the various proteins associated with the spirochete may be regulated by the changes in tick life cycle, changes in conditions during tick feeding (such as temperature, pH , and nutrients) and/or in coordination with the course of infection of the mammal host. Borrelia burgdorferi can colonize multiple tissues, and is capable of attachment to diverse cell types. The expression of decorin-binding protein (Dbp) A and/or DbpB, two B. burgdorferi surface proteins that bind GAGs, is sufficient to convert a high-passage nonadherent B. burgdorferi strain into one that efficiently binds 293 epithelial cells.

    Gen-ID

    1194341

    NCBI Accession

    WP_010890381

    UniProt

    P0CL68

    Pathways

    Regulation of Muscle Cell Differentiation
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