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YBX1 Antikörper (Y Box Binding Protein 1) (AA 276-305) Primary Antibody

YBX1 Reaktivität: Human IF, WB Wirt: Kaninchen Polyclonal RB14114 unconjugated
Produktnummer ABIN390263
$412.50
Zzgl. Versandkosten $45.00
400 μL ABIN390263
400 μL ABIN390263
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 10 bis 11 Werktagen
  • Target
    YBX1
    Bindungsspezifität
    AA 276-305, C-Term
    • 21
    • 17
    • 15
    • 11
    • 8
    • 8
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Reaktivität
    Human
    • 105
    • 66
    • 64
    • 10
    • 8
    • 8
    • 7
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    Wirt
    Kaninchen
    • 97
    • 11
    Klonalität
    Polyklonal
    • 90
    • 18
    Konjugat
    Dieser YBX1 Antikörper ist unkonjugiert
    • 59
    • 7
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Applikation
    Immunofluorescence (IF), Western Blotting (WB)
    • 77
    • 34
    • 25
    • 14
    • 13
    • 12
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Spezifität
    This YBX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283~313 amino acids from the C-terminal region of human YBX1.
    Homologie
    Cow (Bovine),Mouse (Murine),Rat (Rattus),Xenopus laevis
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This YBX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 276-305 AA from the C-terminal region of human YBX1.
    Klon
    RB14114
    Isotyp
    Ig Fraction
  • Applikationshinweise
    WB = 1:1000, IF = 1:10-50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    2 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    YBX1
    Andere Bezeichnung
    YBX1 (YBX1 Antibody Abstract)
    Synonyme
    BP-8, CSDA2, CSDB, DBPB, MDR-NF1, NSEP-1, NSEP1, YB-1, YB1, Byb1, Cbfa, Dbpb, Ef1a, Msy1, Nsep1, Yb1, bp-8, csda2, csdb, dbpb, frgy1, mdr-nf1, nsep-1, nsep1, yb1, 1700102N10Rik, C79409, EF1A, MSY1, dbpB, mYB-1a, nuclease sensitive element binding protein 1, Y-box binding protein 1, Y box binding protein 1, Y-box binding protein 1 S homeolog, nuclease-sensitive element-binding protein 1, Y box protein 1, nsep1, YBX1, Ybx1, ybx1.S, LOC479011
    Hintergrund
    YBX1 binds to splice sites in pre-mRNA and regulates splice site selection. This protein binds and stabilizes cytoplasmic mRNA and contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors. It binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as HLA class II genes. It regulates the transcription of numerous genes and promotes separation of DNA strands that contain mismatches or are modified by cisplatin. It has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro), and it may play a role in DNA repair.
    Synonyms: Nuclease-sensitive element-binding protein 1, Y-box-binding protein 1, Y-box transcription factor, YB-1, CCAAT-binding, transcription factor I subunit A, CBF-A, Enhancer factor I subunit A, EFI-A, DNA-binding protein B, DBPB, YBX1, NSEP1, YB1
    Molekulargewicht
    35924 DA
    Gen-ID
    4904
    UniProt
    P67809
    Pathways
    Regulation of Muscle Cell Differentiation
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