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ITGB1 Antikörper

ITGB1 Reaktivität: Human WB, FACS, IP, Func Wirt: Maus Monoclonal BV7 unconjugated
Produktnummer ABIN960569
  • Target Alle ITGB1 Antikörper anzeigen
    ITGB1 (Integrin beta 1 (ITGB1))
    Reaktivität
    • 212
    • 110
    • 91
    • 21
    • 19
    • 18
    • 18
    • 10
    • 8
    • 8
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 148
    • 76
    • 24
    • 8
    • 8
    • 1
    Maus
    Klonalität
    • 137
    • 124
    • 1
    Monoklonal
    Konjugat
    • 118
    • 24
    • 23
    • 15
    • 10
    • 8
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Dieser ITGB1 Antikörper ist unkonjugiert
    Applikation
    • 132
    • 123
    • 71
    • 54
    • 42
    • 30
    • 28
    • 27
    • 26
    • 21
    • 14
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)
    Spezifität
    This monoclonal antibody (subclass IgG1) binds to human b1-integrin chain present on tumor cells. BV7 is active on HT-29 colon carcinoma cells and on HCCP-2998 tumor cells. BV7 binds to several other tumor cells (MG3 osteosarcoma, A375 melanoma, MHCC-1410 and Lovo colon carcinoma) but does not affect adhesion to endothelial cells.
    Aufreinigung
    Purified
    Immunogen


    Type of Immunogen: Native protein
    Klon
    BV7
    Isotyp
    IgG1
    Top Product
    Discover our top product ITGB1 Primärantikörper
  • Applikationshinweise
    Approved: Flo, Func, IP, WB

    Usage: For flow cytometry and Western blotting dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. For neutralization of biological activity in vitro dilutions have to be made according to the amounts of beta1 integrin to be inactivated.
    Kommentare

    Target Species of Antibody: Human

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    PBS, 0.1 % BSA
    Lagerung
    4 °C
    Informationen zur Lagerung
    4°C. Store undiluted.
  • Target
    ITGB1 (Integrin beta 1 (ITGB1))
    Andere Bezeichnung
    ITGB1 / Integrin Beta 1 / CD29 (ITGB1 Produkte)
    Hintergrund
    Name/Gene ID: ITGB1
    Family: Integrin

    Synonyms: ITGB1, CD29, CD29 antigen, Integrin beta-1, MDF2, MSK12, Integrin VLA-4 beta subunit, VLA-BETA, VLAB, Beta 1 integrin, FNRB, GPIIA, Integrin Beta 1, VLA-4 subunit beta
    Gen-ID
    3688
    UniProt
    P05556
    Pathways
    Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interaktom
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