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ITGB1 Antikörper (AA 25-100)

ITGB1 Reaktivität: Human, Maus, Ratte, Schaf, Kaninchen WB, FACS, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN669216
  • Target Alle ITGB1 Antikörper anzeigen
    ITGB1 (Integrin beta 1 (ITGB1))
    Bindungsspezifität
    • 16
    • 15
    • 13
    • 11
    • 11
    • 9
    • 9
    • 8
    • 6
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 25-100
    Reaktivität
    • 220
    • 111
    • 87
    • 21
    • 20
    • 20
    • 17
    • 12
    • 10
    • 10
    • 10
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Schaf, Kaninchen
    Wirt
    • 158
    • 79
    • 20
    • 8
    • 8
    • 1
    Kaninchen
    Klonalität
    • 145
    • 124
    • 1
    Polyklonal
    Konjugat
    • 119
    • 25
    • 25
    • 16
    • 10
    • 9
    • 9
    • 8
    • 6
    • 6
    • 6
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Dieser ITGB1 Antikörper ist unkonjugiert
    Applikation
    • 135
    • 122
    • 76
    • 50
    • 40
    • 31
    • 29
    • 26
    • 25
    • 20
    • 16
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human, Maus, Kaninchen, Ratte, Schaf
    Homologie
    Dog,Cow,Pig,Horse,Chicken
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Integrin beta 1
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Ji, Zhang, Zhang, Fan, Liu, Yang, Hu, Liu, Dong: "MicroRNA 143-5p regulates alpaca melanocyte migration, proliferation and melanogenesis." in: Experimental dermatology, Vol. 27, Issue 2, pp. 166-171, (2018) (PubMed).

    Zhao, Yu, Yang, Xue, Liu, Jin: "Knockdown of Snail inhibits epithelial-mesenchymal transition of human laryngeal squamous cell carcinoma Hep-2 cells through the vitamin D receptor signaling pathway." in: Biochemistry and cell biology = Biochimie et biologie cellulaire, Vol. 95, Issue 6, pp. 672-678, (2017) (PubMed).

    Qin, Wang, Zheng, Zhou, Zhang, Yang, Zhou: "Concentrated growth factor promotes Schwann cell migration partly through the integrin β1-mediated activation of the focal adhesion kinase pathway." in: International journal of molecular medicine, Vol. 37, Issue 5, pp. 1363-70, (2016) (PubMed).

    Wang, Huang, Tang, Lin, Zhou: "Effects of panax notoginseng saponins on the osteogenic differentiation of rabbit bone mesenchymal stem cells through TGF-β1 signaling pathway." in: BMC complementary and alternative medicine, Vol. 16, Issue 1, pp. 319, (2016) (PubMed).

    Oralova, Matalova, Killinger, Knopfova, Smarda, Buchtova: "Osteogenic Potential of the Transcription Factor c-MYB." in: Calcified tissue international, Vol. 100, Issue 3, pp. 311-322, (2016) (PubMed).

    Fu, Song, Wen, Lu, Cui: "Inositol Hexaphosphate and Inositol Inhibit Colorectal Cancer Metastasis to the Liver in BALB/c Mice." in: Nutrients, Vol. 8, Issue 5, (2016) (PubMed).

    Deng, Chen, Li, Yuan, Li, Ke, Wang, Wu, Luo: "Bone marrow mesenchymal stromal cells with CD47 high expression via the signal transducer and activators of transcription signaling pathway preventing myocardial fibrosis." in: International journal of clinical and experimental pathology, Vol. 8, Issue 9, pp. 10555-64, (2015) (PubMed).

    Jiang, Wang, Zhang, Tang, Ren, Chen: "The role of CD29-ILK-Akt signaling-mediated epithelial-mesenchymal transition of liver epithelial cells and chemoresistance and radioresistance in hepatocellular carcinoma cells." in: Medical oncology (Northwood, London, England), Vol. 32, Issue 5, pp. 141, (2015) (PubMed).

    Lei, Guo, Qiu, Lai, Yang, Widelitz, Chuong, Lian, Yang: "Modulating hair follicle size with Wnt10b/DKK1 during hair regeneration." in: Experimental dermatology, Vol. 23, Issue 6, pp. 407-13, (2014) (PubMed).

    Chen, Shi, Shu, Xie, Yang, Zhang, Ruan, Lin, Lin, Shen, Zhang, Feng, Xie: "The effect of porcine ADM to improve the burn wound healing." in: International journal of clinical and experimental pathology, Vol. 6, Issue 11, pp. 2280-91, (2013) (PubMed).

  • Target
    ITGB1 (Integrin beta 1 (ITGB1))
    Andere Bezeichnung
    Integrin beta 1 (ITGB1 Produkte)
    Synonyme
    CD29 antikoerper, FNRB antikoerper, GPIIA antikoerper, MDF2 antikoerper, MSK12 antikoerper, VLA-BETA antikoerper, VLAB antikoerper, 4633401G24Rik antikoerper, AA409975 antikoerper, AA960159 antikoerper, ENSMUSG00000051907 antikoerper, Fnrb antikoerper, Gm9863 antikoerper, gpIIa antikoerper, cd29 antikoerper, fnrb antikoerper, gpiia antikoerper, itgb1 antikoerper, mdf2 antikoerper, msk12 antikoerper, vla-beta antikoerper, vlab antikoerper, itgb1-a antikoerper, itgb1-b antikoerper, integrin subunit beta 1 antikoerper, integrin beta 1 (fibronectin receptor beta) antikoerper, integrin subunit beta 1 S homeolog antikoerper, integrin beta 1 antikoerper, integrin subunit beta 1 L homeolog antikoerper, ITGB1 antikoerper, Itgb1 antikoerper, itgb1.S antikoerper, LOC100009173 antikoerper, itgb1.L antikoerper
    Hintergrund

    Synonyms: CD29, FNRB, MDF2, VLAB, GPIIA, MSK12, VLA-BETA, Integrin beta-1, Fibronectin receptor subunit beta, Glycoprotein IIa, VLA-4 subunit beta, ITGB1

    Background: Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha-4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha-11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha-4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin alpha-1/beta-1, alpha-2/beta-1, alpha-6/beta-1 and alpha-7/beta-1 are receptors for lamimin. Integrin alpha-4/beta-1 is a receptor for VCAM1. It recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin. Integrin alpha-3/beta-1 is a receptor for epiligrin, thrombospondin and CSPG4. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. Integrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. Isoform beta-1B interferes with isoform beta-1A resulting in a dominant negative effect on cell adhesion and migration (in vitro). In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.

    Gen-ID
    3688
    UniProt
    P05556
    Pathways
    Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interaktom
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