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HCV 1b NS5B Antikörper (AA 111-130)

HCV NS5b Reaktivität: Hepatitis C Virus (HCV) WB, ELISA, IF Wirt: CHO Cells Monoclonal 9A2 unconjugated
Produktnummer ABIN956403
  • Target Alle HCV 1b NS5B (HCV NS5b) Produkte
    HCV 1b NS5B (HCV NS5b) (Hepatitis C Virus NS5b (HCV NS5b))
    Bindungsspezifität
    • 15
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 111-130
    Reaktivität
    • 36
    • 16
    Hepatitis C Virus (HCV)
    Wirt
    • 20
    • 17
    CHO Cells
    Klonalität
    • 20
    • 17
    Monoklonal
    Konjugat
    • 23
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HCV 1b NS5B Antikörper ist unkonjugiert
    Applikation
    • 32
    • 21
    • 17
    • 13
    • 13
    • 8
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    Sequenz
    LSSKAVNHIR SVWKDLLEDT
    Spezifität
    Human, HCV subtype 1b NS5B
    Produktmerkmale
    Partially humanized, chimeric recombinant monoclonal
    Aufreinigung
    purifiedby protein G affinity chromatography
    Immunogen
    Recombinant Hepatitis C Virus subtype 1b nonstructuralprotein 5B (NS5B) RNA-dependent RNA polymerase (RdRp)
    Klon
    9A2
    Isotyp
    IgG1
  • Applikationshinweise
    ELISAtiter 1:1000, Western immunoblotting, reduced conditions, dilution 1:1000, Immunofluorescense 1:1000. Monoclonal antibody working titer has to be established practically for each particular antigen and assay format.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/ml
    Buffer
    PBS pH 7.4, with 0.1%
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Divide antibodyinto aliquots prior usage. Avoid multiple freeze-thaw cycles as productdegradation may result.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    This product isshipped in non-frozen liquid form in ambient conditions
  • Target
    HCV 1b NS5B (HCV NS5b) (Hepatitis C Virus NS5b (HCV NS5b))
    Abstract
    HCV NS5b Produkte
    Substanzklasse
    Viral Protein
    Hintergrund
    Non-structural protein 5B (NS5B)represents the RNA-dependent RNA polymerase (RdRp) of Hepatitis C Virus, whichis a small positive strand RNA virus in the family Flaviviridae. HCV is a major causative agent of acute and chronichepatitis, hepatocellular carcinoma and liver cirrhosis. The single subunitRNA-dependent RNA polymerase is absolutely essential for the viral replication.Antibodyis derived from mouse anti-HCV NS5B monoclonal antoibody 9A2 expressing mousehybridoma culture. cDNA of antibody variable regions were isolated and clonedinto the human IgG1 constant region-containing antibody expression vector.Partially humanized, chimeric antibody was expressed by QMCF CHOEBNALT85 cellline. Antibody is used for high-specific efficient detection of soluble ormembrane-bound proteins fused with 9A2 epitope-tag sequence. For moreinformation please visit: http://icosagen.com/cell-based-assay/qmcf-assay-overview
    UniProt
    Q9WMX2
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