Uroplakin 1B Antikörper (Middle Region)

Produktnummer ABIN955480

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch Uroplakin 1B in WB, FACS und IHC (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Uroplakin 1B Antikörper (Middle Region) (ABIN955480)

Target: Uroplakin 1B (UPK1B)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Uroplakin 1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Uroplakin 1B Antikörper

Bindungsspezifität: AA 166-196, Middle Region

Spezifität: This antibody detects Uroplakin-1b (UPK1B) (Center).

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Protein A column followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 166~196 amino acids from the Central region of human UPK1B

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Details zu Uroplakin 1B

Target: Uroplakin 1B (UPK1B)

Andere Bezeichnung: Uroplakin-1b (UPK1B)

Hintergrund: UPK1B is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions.Synonyms: TSPAN20, Tetraspanin-20, Tspan-20, UP1b, UPIb, Uroplakin Ib

Gen-ID: 7348

NCBI Accession: NP_008883