Uroplakin 1B Antikörper (AA 159-188)

Produktnummer ABIN653680

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Uroplakin 1B in WB, IHC (p) und FACS. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für Uroplakin 1B Antikörper (AA 159-188) (ABIN653680)

Target: Uroplakin 1B (UPK1B)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Uroplakin 1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Klon: RB24302

Produktdetails anti-Uroplakin 1B Antikörper

Bindungsspezifität: AA 159-188

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This UPK1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 159-188 amino acids from the Central region of human UPK1B.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu Uroplakin 1B

Target: Uroplakin 1B (UPK1B)

Andere Bezeichnung: UPK1B

Hintergrund: UPK1B is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions.

Molekulargewicht: 29643

Gen-ID: 7348

NCBI Accession: NP_008883

UniProt: O75841