TRAF4 Antikörper (C-Term)

Produktnummer ABIN955308

Dieses Anti-TRAF4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TRAF4 in WB und EIA. Geeignet für Human.

Kurzübersicht für TRAF4 Antikörper (C-Term) (ABIN955308)

Target: TRAF4 (TNF Receptor-Associated Factor 4 (TRAF4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRAF4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-TRAF4 Antikörper

Bindungsspezifität: AA 426-455, C-Term

Spezifität: This antibody detects TRAF4 / RNF83 (C-term).

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Protein A column followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 426-455 amino acids from the C-terminal region of human TRAF4

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Details zu TRAF4

Target: TRAF4 (TNF Receptor-Associated Factor 4 (TRAF4))

Andere Bezeichnung: TRAF4 / RNF83

Hintergrund: This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined.Synonyms: CART1, Cysteine-rich domain associated with RING and Traf domains protein 1, MLN62, Malignant 62, RING finger protein 83, TNF receptor-associated factor 4

Gen-ID: 9618

NCBI Accession: NP_004286