Stanniocalcin 1 Antikörper (C-Term)
Kurzübersicht für Stanniocalcin 1 Antikörper (C-Term) (ABIN954968)
Target
Alle Stanniocalcin 1 (STC1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 192-221, C-Term
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Spezifität
- This antibody recognizes Stanniocalcin-1 at C-term.
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Kreuzreaktivität (Details)
- Species reactivity (tested):Human
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Aufreinigung
- Purified through a Protein A column followed by peptide affinity purification
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Immunogen
- Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 192-221aa) of human Stanniocalcin-1.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) Sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Stanniocalcin 1 (STC1)
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Andere Bezeichnung
- Stanniocalcin 1 / STC1
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Hintergrund
- The STC1 gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers.Synonyms: STC, STC-1, Stanniocalcin-1
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Gen-ID
- 6781
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NCBI Accession
- NP_003146
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Pathways
- Hormone Activity
Target
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