Der Kaninchen Polyklonal anti-Stanniocalcin 1 Antikörper (ABIN7075723) detektiert spezifisch Stanniocalcin 1 in IHC und IF.
Dieser Antikörper reagiert spezifisch mit Proben aus Maus und Ratte.
STC1
Reaktivität: Human
IHC, ELISA
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
IHC/IF(M,R)1:400-1:800
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
PBS, pH 7.4, 0.02 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Target
Stanniocalcin 1 (STC1)
Andere Bezeichnung
Stanniocalcin 1/STC
Hintergrund
This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers.