Aktivieren Sie Javascript in Ihrem Browser, um unsere Webseite optimal zu nutzen.

SP1 Antikörper (C-Term)

Name: SP1 Antikörper (C-Term)
SKU: ABIN954894
Price: 1044.93 EUR
Availability: InStock

SP1 Reaktivität: Human WB, IF, IHC (p), FACS, EIA Wirt: Kaninchen Polyclonal unconjugated

Western blot analysis in K562 cell line lysates (35ug/lane) using SP1 / TSFP1 Antibody (C-term). (SP1 Antikörper (C-Term))

Flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram) using SP1 / TSFP1 Antibody (C-term), followed by FITC-conjugated goat-anti-rabbit secondary antibodie. (SP1 Antikörper (C-Term))

FACS

Confocal immunofluorescent analysis with WiDr cells using SP1 / TSFP1 Antibody (C-term), followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). (SP1 Antikörper (C-Term))

Immunohistochemistry analysis in human colon carcinoma (Formalin-fixed, Paraffin-embedded) using SP1 / TSFP1 Antibody (C-term), followed by peroxidase conjugation of the secondary antibody and DAB staining. (SP1 Antikörper (C-Term))

IHC (p)

4 Abbildungen

Produktnummer ABIN954894

Datenblatt (PDF)

Target Alle SP1 Antikörper anzeigen

SP1 (Sp1 Transcription Factor (SP1))
Bindungsspezifität
21

12

10

7

4

3

3

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 684-715, C-Term
Reaktivität
88

60

39

11

8

7

6

5

5

5

4

2

2

2

1
Human
Wirt
90

13

3
Kaninchen
Passende Sekundärantikörper
Klonalität
84

22
Polyklonal
Konjugat
72

4

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
Dieser SP1 Antikörper ist unkonjugiert
Applikation
91

46

45

37

21

16

14

13

11

8

4

3

3

1

1

1

1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Spezifität

This antibody recognizes SP1 / TSFP1 at C-term.

Kreuzreaktivität (Details)

Species reactivity (tested):Human

Aufreinigung

Purified through a Protein A column followed by peptide affinity purification

Immunogen

Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 684-715aa) of human SP1 / TSFP1

Isotyp

Ig Fraction

Top Product

Discover our top product SP1 Primärantikörper
anti-Sp1 Transcription Factor (SP1) (AA 677-707), (C-Term) antibody
SP1 Reaktivität: Human WB, IF, IHC (p), FACS Wirt: Kaninchen Polyclonal RB17350 unconjugated

anti-Sp1 Transcription Factor (SP1) (AA 89-198) antibody
SP1 Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 1A5 unconjugated

anti-Sp1 Transcription Factor (SP1) (AA 522-618) antibody
SP1 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 4B11 unconjugated

anti-Sp1 Transcription Factor (SP1) (AA 89-198) antibody
SP1 Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 4H6 unconjugated

anti-Sp1 Transcription Factor (SP1) (C-Term) antibody
SP1 Reaktivität: Human WB, IF, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Sp1 Transcription Factor (SP1) (pThr453) antibody
SP1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Sp1 Transcription Factor (SP1) antibody
SP1 Reaktivität: Human WB, IHC, IF, ChIP Wirt: Kaninchen Monoclonal unconjugated

anti-Sp1 Transcription Factor (SP1) (pThr739) antibody
SP1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Sp1 Transcription Factor (SP1) (AA 420-620) antibody
SP1 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Sp1 Transcription Factor (SP1) (AA 89-199) antibody
SP1 Reaktivität: Human, Maus WB, ELISA, IF Wirt: Maus Monoclonal 4H6 unconjugated

Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

0.25 mg/mL

Buffer

PBS with 0.09 % (W/V) Sodium azide

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Avoid repeated freezing and thawing.

Lagerung

4 °C/-20 °C

Informationen zur Lagerung

Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target

SP1 (Sp1 Transcription Factor (SP1))

Abstract

SP1 Produkte

Hintergrund

Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression.Synonyms: Transcription factor Sp1

Gen-ID

6667

NCBI Accession

NP_003100

Pathways

Regulation of Lipid Metabolism by PPARalpha, Myometrial Relaxation and Contraction