SP1 Antikörper (AA 420-620)
Kurzübersicht für SP1 Antikörper (AA 420-620) (ABIN7270506)
Target
Alle SP1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 420-620
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Verwendungszweck
- SP1 Rabbit pAb
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Sequenz
- LSGQTFTTQA ISQETLQNLQ LQAVPNSGPI IIRTPTVGPN GQVSWQTLQL QNLQVQNPQA QTITLAPMQG VSLGQTSSSN TTLTPIASAA SIPAGTVTVN AAQLSSMPGL QTINLSALGT SGIQVHPIQG LPLAIANAPG DHGAQLGLHG AGGDGIHDDT AGGEEGENSP DAQPQAGRRT RREACTCPYC KDSEGRGSGD P
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 420-620 of human SP1 (NP_612482.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:100 - 1:200,IF,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- SP1 (Sp1 Transcription Factor (SP1))
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Andere Bezeichnung
- SP1
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Hintergrund
- The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene.,SP1,Epigenetics & Nuclear Signaling,Transcription Factors,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial Biogenesis,Nucleotide metabolism,Molecular processes,Neuroscience,Neurodegenerative Diseases,Stem Cells,SP1
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Molekulargewicht
- 75kDa/79kDa/80kDa
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Gen-ID
- 6667
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UniProt
- P08047
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Pathways
- Regulation of Lipid Metabolism by PPARalpha, Myometrial Relaxation and Contraction
Target
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