SH3PXD2A Antikörper (N-Term)

Produktnummer ABIN954793

Produktdetails anti-SH3PXD2A Antikörper

Target: SH3PXD2A (SH3 and PX Domains 2A (SH3PXD2A))

Bindungsspezifität: AA 221-250, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SH3PXD2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: Recognizes SH3PXD2A (N-term) .

Aufreinigung: Protein A column followed by peptide Affinity purification

Immunogen: KLH conjugated synthetic peptide between 221-250 amino acids from the N-terminal region of Human SH3PXD2A Genename: SH3PXD2A

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Details zu SH3PXD2A

Target: SH3PXD2A (SH3 and PX Domains 2A (SH3PXD2A))

Andere Bezeichnung: SH3PXD2A (SH3PXD2A Produkte)

Hintergrund: SH3PXD2A is required for podosome formation, degradation of the extracellular matrix, and for the invasiveness of some cancer cells. Binds phosphatidylinositol 3-phosphate (PtdIns(3)P) and phosphatidylinositol 3,4-biphosphate (PtdIns(3,4)P2). In association with ADAM12, mediates the neurotoxic effect of beta-amyloid peptide.Synonyms: Adaptor protein TKS5, FISH, Five SH3 domain-containing protein, KIAA0418, SH3 and PX domain-containing protein 2A, SH3 multiple domains protein 1, SH3MD1, TKS5

Molekulargewicht: 125289 Da

Gen-ID: 9644

NCBI Accession: NP_055446