SH3PXD2A
Reaktivität: Ratte
IF (cc), IF (p)
Wirt: Kaninchen
Polyclonal
AbBy Fluor® 750
Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.25 mg/mL
Buffer
PBS, 0.09 % (W/V) Sodium Azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Target
SH3PXD2A
(SH3 and PX Domains 2A (SH3PXD2A))
Andere Bezeichnung
SH3PXD2A
Hintergrund
SH3PXD2A is required for podosome formation, degradation of the extracellular matrix, and for the invasiveness of some cancer cells. Binds phosphatidylinositol 3-phosphate (PtdIns(3)P) and phosphatidylinositol 3,4-biphosphate (PtdIns(3,4)P2). In association with ADAM12, mediates the neurotoxic effect of beta-amyloid peptide.Synonyms: Adaptor protein TKS5, FISH, Five SH3 domain-containing protein, KIAA0418, SH3 and PX domain-containing protein 2A, SH3 multiple domains protein 1, SH3MD1, TKS5