SH3PXD2A Antikörper
Kurzübersicht für SH3PXD2A Antikörper (ABIN6135104)
Target
Alle SH3PXD2A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Kreuzreaktivität
- Human, Maus
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- A synthetic peptide of human SH3PXD2A
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- SH3PXD2A (SH3 and PX Domains 2A (SH3PXD2A))
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Andere Bezeichnung
- SH3PXD2A
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Hintergrund
- Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs, NADPH oxidases (NOXs and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of amyloid-beta peptide.,SH3PXD2A,FISH,SH3MD1,TKS5,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Ubiquitin,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,SH3PXD2A
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Molekulargewicht
- 102 kDa/121 kDa/125 kDa
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Gen-ID
- 9644
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UniProt
- Q5TCZ1
Target
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