RAD9A Antikörper

Produktnummer ABIN954440

Der Kaninchen Polyklonal Anti-RAD9A-Antikörper wurde für WB, IHC (p), IF und EIA validiert. Er ist geeignet, RAD9A in Proben von Human zu detektieren.

Kurzübersicht für RAD9A Antikörper (ABIN954440)

Target: RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAD9A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Produktdetails anti-RAD9A Antikörper

Spezifität: This antibody recognizes Human RAD9.

Aufreinigung: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide selected from the Human RAD9A. Genename: RAD9A

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu RAD9A

Target: RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))

Andere Bezeichnung: RAD9A

Hintergrund: This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein is found to possess 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Use of alternative polyA sites has been noted for this gene.Synonyms: Cell cycle checkpoint control protein RAD9A, DNA repair exonuclease rad9 homolog A, EC=3.1.11.2, RAD-9A

Molekulargewicht: 42547 Da

Gen-ID: 5883

NCBI Accession: NP_004575

Pathways: Positive Regulation of Response to DNA Damage Stimulus