Progesterone Receptor Antikörper (Middle Region)

Produktnummer ABIN954305

Der Kaninchen Polyklonal Anti-Progesterone Receptor-Antikörper wurde für WB, IHC (p) und EIA validiert. Er ist geeignet, Progesterone Receptor in Proben von Human zu detektieren.

Kurzübersicht für Progesterone Receptor Antikörper (Middle Region) (ABIN954305)

Target: Progesterone Receptor (PGR)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Progesterone Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-Progesterone Receptor Antikörper

Bindungsspezifität: AA 348-377, Middle Region

Spezifität: This antibody recognizes Human Progesterone receptor (Center).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 348-377 amino acids from the Central region of human Progesterone receptor Genename: PGR

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Progesterone Receptor

Target: Progesterone Receptor (PGR)

Andere Bezeichnung: Progesterone Receptor

Hintergrund: This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform A has not been clearly determined.Synonyms: NR3C3, Nuclear Receptor Subfamily 3 Group C Member 3, PGR, PR

Molekulargewicht: 98981 Da

Gen-ID: 5241

NCBI Accession: NP_000917

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration