PCDHGA1 Antikörper (Middle Region)

Produktnummer ABIN954047

Der Kaninchen Polyklonal anti-PCDHGA1 Antikörper wird verwendet zum Nachweis von PCDHGA1 in Proben von Human. Er wurde validiert für WB, IHC (p) und EIA.

Kurzübersicht für PCDHGA1 Antikörper (Middle Region) (ABIN954047)

Target: PCDHGA1 (Protocadherin gamma A1 (PCDHGA1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCDHGA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-PCDHGA1 Antikörper

Bindungsspezifität: AA 294-323, Middle Region

Spezifität: This antibody recognizes Human PCDHGA1 (Center).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 294-323 amino acids from the Central region of human PCDHGA1

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PCDHGA1

Target: PCDHGA1 (Protocadherin gamma A1 (PCDHGA1))

Andere Bezeichnung: PCDHGA1

Hintergrund: This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.Synonyms: PCDH-gamma-A1, Protocadherin gamma-A1

Molekulargewicht: 90kd

Gen-ID: 56114

NCBI Accession: NP_061735