PCDHGA1 Antikörper (C-Term)
Kurzübersicht für PCDHGA1 Antikörper (C-Term) (ABIN7233054)
Target
Alle PCDHGA1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 808-931, C-Term
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Verwendungszweck
- Anti-Protocadherin γ (pan) Mouse Monoclonal Antibody
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Spezifität
- This antibody recognizes human, mouse, and rat PCDHG-A, B, and C proteins
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Kreuzreaktivität
- Human, Maus, Ratte
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Immunogen
- Fusion protein corresponding to aa 808-931 (C-terminal cytoplasmic constant domain) of mouse PCDHGA1. This sequence is present in all 22 PCDHG proteins.
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Isotyp
- IgG1
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Applikationshinweise
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Immunoblotting: use at 1-2 μg/mL. A band of ~100 kDa is detected.
Immunofluorescence: use at 10 μg/mL.
These are recommended concentrations.
Endusers should determine optimal concentrations for their application. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Rekonstitution
- Dilute in PBS or medium that is identical to that used in the assay system.
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Konzentration
- 1.0 mg/mL
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Buffer
- PBS, pH 7.4, 0.1 % sodium azide, 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- This product is stable for at least one (1) year at -20°C.
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- PCDHGA1 (Protocadherin gamma A1 (PCDHGA1))
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Andere Bezeichnung
- Pcdhga1
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Hintergrund
- Protocadherin γ A1,The protocadherin gamma gene cluster is one of three related clusters tandemly linked on chromosome five. The gamma gene cluster includes 22 genes divided into 3 subfamilies: subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region (which includes 6 cadherin ectodomains and a trans-membrane region). The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins are believed to play a critical role in the establishment and function of specific cell-cell connections in the brain.
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UniProt
- Q91XZ0
Target
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