NUMB Antikörper (N-Term)

Produktnummer ABIN953787

Dieses Anti-NUMB-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von NUMB in WB, IHC (p) und EIA. Geeignet für Human.

Kurzübersicht für NUMB Antikörper (N-Term) (ABIN953787)

Target: NUMB (Numb Homolog (NUMB))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NUMB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-NUMB Antikörper

Bindungsspezifität: AA 1-30, N-Term

Spezifität: This antibody recognizes Human NUMB (N-term).

Aufreinigung: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogen: KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human NUMB

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu NUMB

Target: NUMB (Numb Homolog (NUMB))

Andere Bezeichnung: NUMB

Hintergrund: The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene.Synonyms: Protein S171, Protein numb homolog, h-Numb

Molekulargewicht: 70804 Da

Gen-ID: 8650

NCBI Accession: NP_001005743

Pathways: Cell-Cell Junction Organization