NEIL2 Antikörper (N-Term)

Produktnummer ABIN953644

Produktdetails anti-NEIL2 Antikörper

Target: NEIL2 (Endonuclease 8-like 2 (NEIL2))

Bindungsspezifität: AA 66-96, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NEIL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes Human NEIL2 (N-term).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 66-96 amino acids from the N-terminal region of human NEIL2

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu NEIL2

Target: NEIL2 (Endonuclease 8-like 2 (NEIL2))

Andere Bezeichnung: NEIL2 (NEIL2 Produkte)

Hintergrund: NEIL2 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226].Synonyms: Endonuclease VIII-like 2, NEH2, Nei-like 2

Molekulargewicht: 36826 Da

Gen-ID: 252969

NCBI Accession: NP_001129220

Pathways: DNA Reparatur