MED7 Antikörper (Middle Region)

Produktnummer ABIN953378

Der Kaninchen Polyklonal Anti-MED7-Antikörper wurde für WB, FACS und EIA validiert. Er ist geeignet, MED7 in Proben von Human zu detektieren.

Kurzübersicht für MED7 Antikörper (Middle Region) (ABIN953378)

Target: MED7 (Mediator Complex Subunit 7 (MED7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MED7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Produktdetails anti-MED7 Antikörper

Bindungsspezifität: AA 90-119, Middle Region

Spezifität: This antibody recognizes Human MED7 (Center).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 90-119 amino acids from the Central region of human MED7

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu MED7

Target: MED7 (Mediator Complex Subunit 7 (MED7))

Andere Bezeichnung: MED7

Hintergrund: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].Synonyms: ARC34, Activator-recruited cofactor 34 kDa component, CRSP complex subunit 9, CRSP9, Cofactor required for Sp1 transcriptional activation subunit 9, Mediator complex subunit 7, Mediator of RNA polymerase II transcription subunit 7, RNA polymerase transcriptional regulation mediator subunit 7 homolog, Transcriptional coactivator CRSP33

Molekulargewicht: 27245 Da

Gen-ID: 9443

NCBI Accession: NP_001094286

Pathways: Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha