Mediator Complex Subunit 7 (MED7) (Middle Region) Antikörper

Details zu Produkt Nr. ABIN2787458, Anbieter: Anmelden zum Anzeigen
Antigen
  • ARC34
  • CRSP33
  • CRSP9
  • 1110063B05Rik
  • Crsp33
  • Crsp9
  • crsp9
  • wu:fd99d12
  • zgc:56241
  • crsp9-A
  • med7-a
  • mediator complex subunit 7
  • mediator complex subunit 7 L homeolog
  • mediator complex subunit
  • mediator complex subunit Med7
  • MED7
  • Med7
  • med7
  • med7.L
Epitop
Middle Region
15
10
8
8
7
6
4
4
4
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Zebrafisch (Danio rerio)
68
22
21
8
7
6
6
6
5
4
3
3
3
2
2
Wirt
Kaninchen
47
21
Klonalität
Polyklonal
Konjugat
Unkonjugiert
4
4
4
3
3
3
1
1
1
1
1
1
1
1
1
1
1
Applikation
Chromatin Immunoprecipitation (ChIP), Western Blotting (WB)
52
26
18
13
6
3
3
2
1
1
1
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen The immunogen is a synthetic peptide directed towards the middle region of human MED7
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN979958.
Sequenz KRQRLETAER FQKHLERVIE MIQNCLASLP DDLPHSEAGM RVKTEPMDAD
Homologie Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
Produktmerkmale This is a rabbit polyclonal antibody against MED7. It was validated on Western Blot.
Reinigung Affinity Purified
Andere Bezeichnung MED7 (MED7 Antibody Abstract)
Hintergrund The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. Two transcript variants encoding the same protein have been found for this gene.
Alias Symbols: CRSP33, CRSP9, MGC12284, ARC34
Protein Interaction Partner: HAUS1, CDK8, CDK19, MED13, MED19, MED26, EPAS1, MED6, UBE2I, UL48, SUMO2, UBC, CTDP1, MED10, MED25, MED15, MED14, VDR, SREBF1, RELA, PARP1, ZSCAN1, TRIM15, RHOXF2, PCBD2, MED31, TRIM29, RBFOX2, IKBKG, LZTR1, PML, MED9, MED8, HGS, MED1, HNF4A, ESR2, ESR1,
Protein Size: 233
Molekulargewicht 27 kDa
Gen-ID 9443
NCBI Accession NM_004270, NP_004261
UniProt O43513
Pathways Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 233 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Western Blotting (WB) image for anti-Mediator Complex Subunit 7 (MED7) (Middle Region) antibody (ABIN2787458) WB Suggested Anti-MED7 Antibody Titration: 0.2-1 ug/ml
Positive Control:...
Western Blotting (WB) image for anti-Mediator Complex Subunit 7 (MED7) (Middle Region) antibody (ABIN2787458) WB Suggested Anti-MED7
Antibody Titration: 0.2-1 µg/mL
Positive Control...
Chromatin Immunoprecipitation (ChIP) image for anti-Mediator Complex Subunit 7 (MED7) (Middle Region) antibody (ABIN2787458) Quiescent human colon carcinoma HCT116 cultures were treated with 10 % FBS for three ...
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