KNG1 Antikörper (N-Term)
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- Target Alle KNG1 Antikörper anzeigen
- KNG1 (Kininogen 1 (KNG1))
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Bindungsspezifität
- AA 145-174, N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser KNG1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody recognizes Human Kininogen-1 (N-term).
- Aufreinigung
- Protein A column, followed by peptide affinity purification
- Immunogen
- KLH conjugated synthetic peptide between 145-174 amino acids from the N-terminal region of Human Kininogen-1 Genename: KNG1
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product KNG1 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.25 mg/mL
- Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- KNG1 (Kininogen 1 (KNG1))
- Andere Bezeichnung
- Kininogen-1 (KNG1 Produkte)
- Hintergrund
- This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.Synonyms: Alpha-2-thiol proteinase inhibitor, BDK, Fitzgerald factor, High molecular weight kininogen, KNG, KNG1, Williams-Fitzgerald-Flaujeac factor
- Molekulargewicht
- 71957 Da
- Gen-ID
- 3827
- NCBI Accession
- NP_000884
- Pathways
- ACE Inhibitor Pathway, Glycosaminoglycan Metabolic Process
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