KDM4C Antikörper (C-Term)

Produktnummer ABIN952976

Der Kaninchen Polyklonal Anti-KDM4C-Antikörper wurde für WB, FACS und EIA validiert. Er ist geeignet, KDM4C in Proben von Human zu detektieren.

Kurzübersicht für KDM4C Antikörper (C-Term) (ABIN952976)

Target: KDM4C (Lysine (K)-Specific Demethylase 4C (KDM4C))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KDM4C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Produktdetails anti-KDM4C Antikörper

Bindungsspezifität: AA 1030-1056, C-Term

Spezifität: This antibody recognizes Human JMJD2C / KDM4C (C-term).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 1030-1056 amino acids from the C-terminal region of human JMJD2C Genename: KDM4C

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu KDM4C

Target: KDM4C (Lysine (K)-Specific Demethylase 4C (KDM4C))

Andere Bezeichnung: JMJD2C / KDM4C

Hintergrund: This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants.Synonyms: GASC-1 protein, GASC1, Gene amplified in squamous cell carcinoma 1 protein, JHDM3C, JmjC domain-containing histone demethylation protein 3C, Jumonji domain-containing protein 2C, KIAA0780, Lysine-specific demethylase 4C

Molekulargewicht: 119982 Da

Gen-ID: 23081

NCBI Accession: NP_001140166

Pathways: Nuclear Hormone Receptor Binding, Warburg Effekt