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INHBB Antikörper (C-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch INHBB in WB, IHC (p) und EIA. Er zeigt eine Reaktivität gegenüber Human und Maus und wurde in 1 Publikation erwähnt.
Produktnummer ABIN952903

Kurzübersicht für INHBB Antikörper (C-Term) (ABIN952903)

Target

Alle INHBB Antikörper anzeigen
INHBB (Inhibin, beta B (INHBB))

Reaktivität

  • 71
  • 38
  • 28
  • 19
  • 10
  • 1
  • 1
  • 1
Human, Maus

Wirt

  • 91
  • 22
Kaninchen

Klonalität

  • 89
  • 24
Polyklonal

Konjugat

  • 58
  • 24
  • 13
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser INHBB Antikörper ist unkonjugiert

Applikation

  • 94
  • 62
  • 43
  • 28
  • 25
  • 8
  • 6
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • Bindungsspezifität

    • 15
    • 9
    • 7
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 376-404, C-Term

    Spezifität

    This antibody recognizes Human and Mouse INHBB (C-term).

    Produktmerkmale

    Purified Ig fraction

    Aufreinigung

    Protein A column, followed by peptide affinity purification

    Immunogen

    KLH conjugated synthetic peptide between 376-404 amino acids from the C-terminal region of human INHBB

    Isotyp

    Ig Fraction
  • Applikationshinweise

    Suggested dilutions:
    ELISA: 1/1000.
    Western Blot: 1/100-1/500.
    Immunohistochemistry on Paraffin Sections: 1/10-1/50.

    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.25 mg/mL

    Buffer

    PBS containing 0.09 % (W/V) Sodium Azide as preservative

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Zhong, Pons, Poirier, Jiang, Liu, Sandusky, Shahda, Nakeeb, Schmidt, House, Ceppa, Zyromski, Liu, Jiang, Couch, Koniaris, Zimmers: "The systemic activin response to pancreatic cancer: implications for effective cancer cachexia therapy." in: Journal of cachexia, sarcopenia and muscle, Vol. 10, Issue 5, pp. 1083-1101, (2020) (PubMed).

  • Target

    INHBB (Inhibin, beta B (INHBB))

    Andere Bezeichnung

    Inhibin beta B Chain (INHBB)

    Hintergrund

    The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion.Synonyms: Activin B, Activin beta-B chain

    Molekulargewicht

    45122 Da

    Gen-ID

    3625

    NCBI Accession

    NP_002184

    UniProt

    P09529

    Pathways

    Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion
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