HDAC11 Antikörper (Middle Region)

Produktnummer ABIN952697

Der Kaninchen Polyklonal Anti-HDAC11-Antikörper wurde für WB und EIA validiert. Er ist geeignet, HDAC11 in Proben von Human und Maus zu detektieren.

Kurzübersicht für HDAC11 Antikörper (Middle Region) (ABIN952697)

Target: HDAC11 (Histone Deacetylase 11 (HDAC11))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HDAC11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-HDAC11 Antikörper

Bindungsspezifität: AA 196-226, Middle Region

Spezifität: This antibody recognizes Human and Mouse HDAC11 (Center).

Kreuzreaktivität (Details): Species reactivity (expected):Monkey.

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 196-226 amino acids from the Central region of human HDAC11

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu HDAC11

Target: HDAC11 (Histone Deacetylase 11 (HDAC11))

Andere Bezeichnung: HDAC11

Hintergrund: This gene encodes a class IV histone deacetylase. The encoded protein is localized to the nucleus and may be involved in regulating the expression of interleukin 10. Alternative splicing results in multiple transcript variants. Function: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Cellular Location: Nucleus. Note=Predominantly nuclear. Tissue Location: Weakly expressed in most tissues. Strongly expressed in brain, heart, skeletal muscle, kidney and testisSynonyms: HD11, Histone deacetylase 11

Molekulargewicht: 39183 Da

Gen-ID: 79885

NCBI Accession: NP_079103