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HDAC11 Antikörper (N-Term)

HDAC11 Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3043840
  • Target Alle HDAC11 Antikörper anzeigen
    HDAC11 (Histone Deacetylase 11 (HDAC11))
    Bindungsspezifität
    • 9
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 47-81, N-Term
    Reaktivität
    • 59
    • 43
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 69
    • 5
    Kaninchen
    Klonalität
    • 70
    • 4
    Polyklonal
    Konjugat
    • 37
    • 7
    • 6
    • 6
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HDAC11 Antikörper ist unkonjugiert
    Applikation
    • 64
    • 43
    • 32
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Verwendungszweck
    Rabbit IgG polyclonal antibody for Histone deacetylase 11(HDAC11) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Sequenz
    NFLKEEKLLS DSMLVEAREA SEEDLLVVHT RRYLN
    Kreuzreaktivität (Details)
    No cross reactivity with other proteins.
    Produktmerkmale
    Rabbit IgG polyclonal antibody for Histone deacetylase 11(HDAC11) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: histone deacetylase 11
    Protein Name: Histone deacetylase 11
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence at the N-terminus of human HDAC11 (47-81aa NFLKEEKLLSDSMLVEAREASEEDLLVVHTRRYLN), different from the related mouse sequence by one amino acid.
    Isotyp
    IgG
    Top Product
    Discover our top product HDAC11 Primärantikörper
  • Applikationshinweise
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Target
    HDAC11 (Histone Deacetylase 11 (HDAC11))
    Andere Bezeichnung
    HDAC11 (HDAC11 Produkte)
    Synonyme
    CG31119 antikoerper, DHDACX antikoerper, Dmel\\CG31119 antikoerper, HDAC11 antikoerper, HDACX antikoerper, dHDAC11 antikoerper, dmHDA403 antikoerper, zgc:91942 antikoerper, HD11 antikoerper, histone deacetylase 11 antikoerper, Histone deacetylase 11 antikoerper, hypothetical protein antikoerper, HDAC11 antikoerper, hdac11 antikoerper, CpipJ_CPIJ001619 antikoerper, Bm1_15905 antikoerper, LOAG_18214 antikoerper, Hdac11 antikoerper
    Hintergrund
    Histone deacetylase 11 is a 39 kDa histone deacetylase enzyme that in humans is encoded by the HDAC11 gene on chromosome 3 in humans and chromosome 6 in mice. This gene encodes a class IV histone deacetylase. And the encoded protein is localized to the nucleus and may be involved in regulating the expression of interleukin 10. Alternative splicing results in multiple transcript variants. HDAC11 expression is normally found in brain and testis tissue, but upregulation of HDAC11 expression has also been seen in various cancer cells. In addition, HDAC11 has been shown to be a negative regulator of IL-10 production in antigen presenting cells. It has also been shown that inhibition of HDAC11 results in increased expression of OX40L in Hodgkin lymphoma cells.

    Synonyms: FLJ22237 antibody|HD 11 antibody|HD11 antibody|HDA11_HUMAN antibody|HDAC 11 antibody|HDAC11 antibody|Histone deacetylase 11 antibody
    Gen-ID
    79885
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