Glypican 3 Antikörper (C-Term)

Produktnummer ABIN952555

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Glypican 3 in WB und EIA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Glypican 3 Antikörper (C-Term) (ABIN952555)

Target: Glypican 3 (GPC3)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Glypican 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-Glypican 3 Antikörper

Bindungsspezifität: AA 464-494, C-Term

Spezifität: This antibody reacts to GPC3.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 464-494 amino acids from the C-terminal region of human GPC3

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Glypican 3

Target: Glypican 3 (GPC3)

Andere Bezeichnung: Glypican-3 / GPC3

Hintergrund: Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.Synonyms: GTR2-2, Intestinal protein OCI-5, MXR7, OCI5

Molekulargewicht: 65563 Da

Gen-ID: 2719

NCBI Accession: NP_004475

Pathways: Glycosaminoglycan Metabolic Process