GLP2R Antikörper (Middle Region)

Produktnummer ABIN952529

Der Kaninchen Polyklonal anti-GLP2R Antikörper wird verwendet zum Nachweis von GLP2R in Proben von Human. Er wurde validiert für WB und EIA.

Kurzübersicht für GLP2R Antikörper (Middle Region) (ABIN952529)

Target: GLP2R (Glucagon-Like Peptide 2 Receptor (GLP2R))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLP2R Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-GLP2R Antikörper

Bindungsspezifität: AA 219-248, Middle Region

Spezifität: This antibody recognizes Human GLP2R (Center).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 219-248 amino acids from the Central region of human GLP2R

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu GLP2R

Target: GLP2R (Glucagon-Like Peptide 2 Receptor (GLP2R))

Andere Bezeichnung: GLP2 Receptor

Hintergrund: The GLP2 receptor (GLP2R) is a G protein-coupled receptor superfamily member closely related to the glucagon receptor ans GLP1 receptor. Glucagon-like peptide-2 (GLP2) is a 33-amino acid proglucagon-derived peptide produced by intestinal enteroendocrine cells. Like glucagon-like peptide-1 (GLP1) and glucagon itself, it is derived from the proglucagon peptide encoded by the GCG gene. GLP2 stimulates intestinal growth and upregulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. Moreover, GLP2 prevents intestinal hypoplasia resulting from total parenteral nutrition. GLP2R, a G protein-coupled receptor superfamily member is expressed in the gut and closely related to the glucagon receptor (GCGR) and the receptor for GLP1 (GLP1R). [provided by RefSeq].Synonyms: GLP-2-R, GLP-2R, GLP2R, Glucagon-like peptide 2 receptor

Molekulargewicht: 63001 Da

Gen-ID: 9340

NCBI Accession: NP_004237

Pathways: Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, cAMP Metabolic Process, Feeding Behaviour