FZD6 Antikörper (Middle Region)

Produktnummer ABIN952410

Dieses Anti-FZD6-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von FZD6 in WB und EIA. Geeignet für Human.

Kurzübersicht für FZD6 Antikörper (Middle Region) (ABIN952410)

Target: FZD6 (Frizzled Family Receptor 6 (FZD6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FZD6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-FZD6 Antikörper

Bindungsspezifität: AA 493-520, Middle Region

Spezifität: This antibody recognizes Human FZD6 (Center).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 493-520 amino acids from the Central region of human FZD6

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu FZD6

Target: FZD6 (Frizzled Family Receptor 6 (FZD6))

Andere Bezeichnung: FZD6

Hintergrund: This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants.Synonyms: Frizzled-6, Fz-6, hFz6

Molekulargewicht: 79292 Da

Gen-ID: 8323

NCBI Accession: NP_001158087

Pathways: WNT Signalweg, Tube Formation