FUS Antikörper (C-Term)

Produktnummer ABIN952406

Der Kaninchen Polyklonal Anti-FUS Antikörper wurde für WB, IF, FACS, IHC (p) und EIA validiert. Er ist geeignet, FUS in Proben von Human und Maus zu detektieren.

Kurzübersicht für FUS Antikörper (C-Term) (ABIN952406)

Target: FUS (Fused in Sarcoma (FUS))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FUS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-FUS Antikörper

Bindungsspezifität: AA 506-534, C-Term

Spezifität: This antibody recognizes Human and Mouse FUS (C-term).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 506-534 amino acids from the C-terminal region of human FUS

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu FUS

Target: FUS (Fused in Sarcoma (FUS))

Andere Bezeichnung: FUS / TLS

Hintergrund: This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.Synonyms: 75 kDa DNA-pairing protein, Oncogene FUS, Oncogene TLS, POMp75, RNA-binding protein FUS, Translocated in liposarcoma protein

Molekulargewicht: 53426 Da

Gen-ID: 2521

NCBI Accession: NP_001164105