EPOR Antikörper (Middle Region)

Produktnummer ABIN952118

Der Kaninchen Polyklonal Anti-EPOR Antikörper wurde für WB, FACS und EIA validiert. Er ist geeignet, EPOR in Proben von Human zu detektieren.

Kurzübersicht für EPOR Antikörper (Middle Region) (ABIN952118)

Target: EPOR (Erythropoietin Receptor (EPOR))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EPOR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Produktdetails anti-EPOR Antikörper

Bindungsspezifität: AA 328-357, Middle Region

Spezifität: This antibody recognizes Human Erythropoietin receptor (Center).

Aufreinigung: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 328-357 amino acids from the Central region of Human Erythropoietin receptor Genename: EPOR

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu EPOR

Target: EPOR (Erythropoietin Receptor (EPOR))

Andere Bezeichnung: Erythropoietin Receptor

Hintergrund: This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.Synonyms: EPO-R, EPOR

Molekulargewicht: 55065 Da

Gen-ID: 2057

NCBI Accession: NP_000112

Pathways: JAK-STAT Signalweg