E2F2 Antikörper (Middle Region)
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- Target Alle E2F2 Antikörper anzeigen
- E2F2 (E2F Transcription Factor 2 (E2F2))
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Bindungsspezifität
- AA 265-297, Middle Region
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser E2F2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody recognizes Human and Mouse E2F2 (Center).
- Aufreinigung
- Affinity Chromatography on Protein A
- Immunogen
- KLH conjugated synthetic peptide between 265-297 amino acids from the Central region of Human E2F2
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product E2F2 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.25 mg/mL
- Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- E2F2 (E2F Transcription Factor 2 (E2F2))
- Andere Bezeichnung
- E2F2 (E2F2 Produkte)
- Synonyme
- E2F-2 antikoerper, CG1071 antikoerper, Dmel\\CG1071 antikoerper, E2F antikoerper, E2F2 antikoerper, dE2F-2 antikoerper, dE2F2 antikoerper, dE2f2 antikoerper, de2f2 antikoerper, e2f2 antikoerper, 9230110J10 antikoerper, E130207A07 antikoerper, fb40b03 antikoerper, wu:fb40b03 antikoerper, E2F transcription factor 2 antikoerper, si:ch211-160f23.5 antikoerper, E2F2 antikoerper, E2f2 antikoerper, si:ch211-160f23.5 antikoerper
- Hintergrund
- E2F2 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F3, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner, and it exhibits overall 46 % amino acid identity to E2F1. [provided by RefSeq].Synonyms: E2F transcription factor 2, E2F-2, Transcription factor E2F2
- Molekulargewicht
- 47506 Da
- Gen-ID
- 1870
- NCBI Accession
- NP_004082
- Pathways
- Zellzyklus, Mitotic G1-G1/S Phases, DNA Replication
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