Dynamitin Antikörper (Middle Region)

Produktnummer ABIN952005

Dieses Anti-Dynamitin-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Dynamitin in WB, IHC (p) und EIA. Geeignet für Human.

Kurzübersicht für Dynamitin Antikörper (Middle Region) (ABIN952005)

Target: Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Dynamitin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-Dynamitin Antikörper

Bindungsspezifität: AA 191-219, Middle Region

Spezifität: This antibody recognizes Human Dynactin subunit 2 (Center).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 191-219 amino acids from the Central region of Human Dynactin subunit 2. Genename: DCTN2

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Dynamitin

Target: Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))

Andere Bezeichnung: Dynactin Subunit 2

Hintergrund: This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place.Synonyms: 50 kDa dynein-associated polypeptide, DCTN2, DCTN50, Dynactin 2, Dynactin complex 50 kDa subunit, RBP50, p50 dynamitin

Molekulargewicht: 44231 Da

Gen-ID: 10540

NCBI Accession: NP_006391

Pathways: M Phase, Ribonucleoprotein Complex Subunit Organization