DUOX2 Antikörper (Middle Region)

Produktnummer ABIN951993

Der Kaninchen Polyklonal anti-DUOX2 Antikörper (ABIN951993) detektiert spezifisch DUOX2 in WB, FACS und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für DUOX2 Antikörper (Middle Region) (ABIN951993)

Target: DUOX2 (Dual Oxidase 2 (DUOX2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DUOX2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Produktdetails anti-DUOX2 Antikörper

Bindungsspezifität: AA 520-550, Middle Region

Spezifität: This antibody recognizes Human Dual oxidase 2 (Center).

Aufreinigung: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 520-550 amino acids from the Central region of human DUOX2

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu DUOX2

Target: DUOX2 (Dual Oxidase 2 (DUOX2))

Andere Bezeichnung: Dual Oxidase 2

Hintergrund: The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX1. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain.Synonyms: LNOX2, Large NOX 2, Long NOX 2, NADH/NADPH thyroid oxidase p138-tox, NADPH oxidase/peroxidase DUOX2, NADPH thyroid oxidase 2, THOX2, Thyroid oxidase 2, p138 thyroid oxidase

Molekulargewicht: 175364 Da

Gen-ID: 50506

NCBI Accession: NP_054799

Pathways: Thyroid Hormone Synthesis