TdT Antikörper (C-Term)

Produktnummer ABIN951960

Dieses Anti-TdT-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TdT in WB und EIA. Geeignet für Human.

Kurzübersicht für TdT Antikörper (C-Term) (ABIN951960)

Target: TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TdT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-TdT Antikörper

Bindungsspezifität: AA 445-475, C-Term

Spezifität: This antibody detects DNTT / TDT (C-term).

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Protein A column followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 445-475 amino acids from the C-terminal region of human TdT

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Details zu TdT

Target: TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))

Andere Bezeichnung: DNTT / TDT

Hintergrund: This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.Synonyms: DNA nucleotidylexotransferase, Terminal addition enzyme, Terminal deoxynucleotidyltransferase, Terminal transferase

Gen-ID: 1791

NCBI Accession: NP_001017520

Pathways: DNA Reparatur