LIG3 Antikörper (C-Term)

Produktnummer ABIN951931

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch LIG3 in WB und EIA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für LIG3 Antikörper (C-Term) (ABIN951931)

Target: LIG3 (Ligase III, DNA, ATP-Dependent (LIG3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LIG3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-LIG3 Antikörper

Bindungsspezifität: AA 792-822, C-Term

Spezifität: This antibody recognizes Human DNA ligase 3 (C-term).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 792-822 amino acids from the C-terminal region of Human DNA ligase 3 Genename: LIG3

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu LIG3

Target: LIG3 (Ligase III, DNA, ATP-Dependent (LIG3))

Andere Bezeichnung: DNA Ligase 3

Hintergrund: This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized.Synonyms: DNA ligase 3, DNA ligase III, EC=6.5.1.1, LIG-3, LIG3, Polydeoxyribonucleotide synthase [ATP] 3

Molekulargewicht: 112907 Da

Gen-ID: 3980

NCBI Accession: NP_002302

Pathways: DNA Reparatur